Delivered to a hospital. Examination revealed inherited disturbance of neutral amino acid
Transporting in the bowels. These symptoms were caused by the deficiency of the following
Vitamin:
A Niacin
B Pantothenic acid
C Vitamin A
D Cobalamin
E Biotin
151
A 5-month-old boy was hospitalized for tonic convulsions. He has a life-time history of this
Disease. Examination revealed coarse hair, thinned and fragile nails, pale and dry skin. In blood:
Calcium - 1,5 millimole/l, phosphor - 1,9 millimole/l. These changes are associated with:
A Hypoparathyroidism
B Hyperparathyroidism
C Hyperaldosteronism
D Hypoaldosteronism
E Hypothyroidism
152
During hypersensitivity test a patient got subcutaneous injection of an antigen which caused
Reddening of skin, edema, pain as a result of histamine action. This biogenic amine is generated
As a result of transformation of the following histidine amino acid:
A Decarboxylation
B Methylation
C Phosphorylation
D Isomerization
E Deaminization
153
A patient with suspected diagnosis "progressing muscular dystrophy" got his urine tested. What
Compound will confirm this diagnosis if found in urine?
A Kreatine
B Collagen
C Porphyrin
D Myoglobin
E Calmodulin
154
Cytogenetic examination of a patient with dysfunction of the reproductive system revealed
Normal karyotype 46, ХУ in some cells, but most cells have Klinefelter's syndrome karyotype -
ХХУ . Such phenomenon of cell inhomogeneity is called:
A Mosaicism
B Inversion
C Transposition
D Duplication
E Heterogeneity
155
An oncological patient had been administered methotrexate. With time target cells of the tumour
Lost sensitivity to this drug. At the same time the change in gene expression of the following
Enzyme is observed:
A Dehydropholate reductase
B Thiaminase
C Deaminase
D Pholate oxidase
E Pholate decarboxylase
156
A patient complained about dizziness, memory impairment, periodical convulsions. It was
Revealed that these changes were caused by a product of decarboxylation of glutamic acid.
Name this product:
A GABA
B Pyridoxal phosphate
C TDP
D ATP
E THFA
157
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A sportsman needs to improve his sporting results. He was recommended to take a preparation
That contains carnitine. What process is activated the most by this compound?
A Fatty acids transporting
B Amino acids transporting
C Calcium ions transporting
D Glucose transporting
E Vitamin K transporting
158
A doctor examined a child and revealed symptoms of rachitis. Development of this desease was
Caused by deficiency of the following compound:
A 1,25 [ ОН ]-dichydroxycholecalciferol
B Biotin
C Tocopherol
D Naphtaquinone
E Retinol
159
Laboratory examination of a child revealed increased concentration of leucine, valine,
Isoleucine and their ketoderivatives in blood and urine. Urine smelt of maple syrup. This disease
Is characterized by the deficit of the following enzyme:
A Dehydrogenase of branched amino acids
B Aminotransferase
C Glucose-6-phosphatase
D Phosphofructokinase
E Phosphofructomutase
160
A 9-month-old infant is fed with artificial formulas with unbalanced vitamin B6 concentration.
The infant presents with pellagral dermatitis, convulsions, anaemia. Convulsion development
Might be caused by the disturbed formation of:
A GABA
B Histamine
C Serotonin
D DOPA
E Dopamine
161
It was found out that some compounds, for instance fungi toxins and some antibiotics can inhibit
Activity of RNA-polymerase. What process will be disturbed in a cell in case of inhibition of
This enzyme?
A Transcription
B Processing
C Replication
D Translation
E Reparation
162
When blood circulation in the damaged tissue is restored, then lactate accumulation comes to a
Stop and glucose consumption decelerates. These metabolic changes are caused by activation
Of the following process:
A Aerobic glycolysis
B Anaerobic glycolysis
C Lipolysis
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D Gluconeogenesis
E Glycogen biosynthesis
163
During starvation muscle proteins break up into free amino acids. These compounds will be the
Most probably involved into the following process:
A Gluconeogenesis in liver
B Gluconeogenesis in muscles
C Synthesis of higher fatty acids
D Glycogenolysis
E Decarboxylation
164
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