Destruction of the tissue structure of the node, absence of the lymph follicles, sclerotic and



Necrosis parts, cell constitution of the node is polymorphous, lymphocites, eosinophiles,

Atypical cells of the large size with multiple-lobule nuclei (Beresovsky-Shternberg cells) and

Onenucleus cells of the large size are present. What is the most likely diagnosis?

A Lymphogranulomatous

B Acute lympholeucosis

C Chronic lympholeucosis

D Berkitt's lymphoma

E Fungous mycosis

      23

A female patient suffering from bronchial asthma had got a viral infection that provoked status

Asthmaticus with fatal outcome. Histological examination of lungs revealed spasm and edema of

Bronchioles, apparent infiltration of their walls with lymphocytes, eosinophils and other

Leukocytes; labrocyte degranulation. What mechanism of hypersensitivity underlies the

Described alterations?

A Reagin reaction

B Inflammatory

C Autoimmune

D Immune complex

E Immune cytolysis

      24

On autopsy of the 40-year-old woman suffering from rheumatic arthritis, the enlarged solid

Spleen was revealed. On section its tissue is of the mahogany color with enlarged follicles, which

Look like semi-transparent grayish-whitish grains. What pathological process is the most likely?

A Sago spleen

B Glaze spleen

C Waxy spleen

D Hyaline spleen

E Porphyric spleen

      25

Local lymphonodules enlarged near the infected wound. Increased amount of macrophages,

Lymphocytes, lymphatic follicles in the cortical layer and large amount of plasma cells were

Revealed on histological examination. What process in the lymphatic nodules represent these

Histological changes?

A Antigen stimulation

B Acquired insufficiency of the lymphoid tissue

C Innate insufficiency of the lymphoid tissue

D Tumour transformation

E Hypersensibility reaction

      26

On autopsy of the man with alcohol abuse for a long time it was revealed: dense, small-knobby,

Small size liver. Microscopically: small pseudo-lobules, divided with thin layers of connective

Tissue with lymphomacrophagial infiltrates; hepatocytes in the state of globular fatty dystrophy.

What is the most likely diagnosis?

A Alcohol cirrhosis

B Chronic active alcohol hepatitis

C Chronic persistent alcohol hepatitis

D Toxic liver dystrophy

E Fatty hepatosis

      27

An 8-year-old child was admitted to the infectious department with fever (up to 38oC) and

Punctuate bright-red skin rash. The child was diagnosed as having scarlet fever. Objectively:

Mucous membrane of pharynx is apparently hyperaemic and edematic, the tonsils are enlarged

And have dull yellowish-grey foci with some black areas. What inflammation is the reason for the

Pharynx alterations?

A Purulent necrotic

B Fibrinous

C Haemorrhagic

D Serous

E Catarrhal

      28

A 30-year-old patient with bacteriologically proved dysentery developed the signs of paraproctitis. What is the stage of local changes in this patient?

A Ulceration stage

B Fibrinous colitis

C Follicular colitis

D Catarrhal colitis

E Healing of the ulcers stage

      29

A patient who has been abusing tobacco smoking for a long time has got cough accompanied by

Excretion of viscous mucus; weakness after minor physical stress, pale skin. The patient has

Also lost 12,0 kg of body weight. Endoscopic examination of biosy material his illness was

Diagnosed as squamous cell carcinoma. Name a pathological process that preceded formation

Of the tumour:

A Metaplasia

B Hypoplasia

C Hyperplasia

D Necrosis

E Sclerosis

      30

Diagnostic scraping was performed to the woman with dysfunctional uterine bleeding. Multiple

Convoluted glands, ganglially dilated cavities of some glands were revealed histologically in the

Scrape. Name the type of general pathological process.

A Glandulo-gangliac hyperplasia

B Atrophy

C Metaplasia

D Displasia

E Hypertrophic excrescence

      31

Tuberculine was injected intracutaneously to the child for tuberculin test. Marked hyperemia,

Tissue infiltration developed on the place of injection in 24 hours. What mechanism caused

These modifications?

A Cells cytotoxity

B Reagin type cytotoxity

C Antibody cytotoxity

D Granuloma formation

E Immunocomplex cytotoxity

      32


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